2025
1. Elamin I, Meghna R, Figliozzi R, Maahs CJ, Balish M, Hsia V, Paula A, Fan J. Protocol for Extracting Circulating Cell-Free DNA from Murine Saliva: Insights into Oral and Systemic Disease Research. bioRxiv. doi: https://doi.org/10.1101/2025.03.31.
2023-2024
1. Kang M, Li Z, Chang I, Xu C, Chiang M, Kim L, Wu Y, Fan J, Aghaloo T, Lee M. Phosphatidylserine‐Incorporated Exosome Mimetics Encapsulating CXCR3 Antagonist Alleviate Osteoporosis. Advanced Functional Materials, 2402521, 2024.
2. Fan J, Zhang X, Kang M, Lee CS, Kim L, Hadaya D, Aghaloo TL, Lee M. Complementary modulation of BMP signaling improves bone healing efficiency. Biomaterials. 302, 122335, 2023.
3. Lee CS*, Fan J*, Hwang HS, Kim S, Chen C, Kang M, Aghaloo T, James A, Lee M. Bone-targeting Exosome Mimetics Engineered by Biorthogonal Surface Functionalization for Bone Tissue Engineering. Nano Lett. 23(4):1202-1210, 2023. *Co-first authors
2014-2022
1. Zhang X*, Fan J*, Chen C, Aghaloo T, Lee M. Co-delivery of Simvastatin and Demineralized Bone Matrix Hierarchically from Nanosheet-based Supramolecular Hydrogels for Osteogenesis. J. Mater. Chem. B, 9, 7741-7750, 2021. *Co-first author
2. Chen C, Rahnama M, Kim S, Lee CS, Zhang X, Aghaloo T, Fan J*, Lee M*. Enhanced Osteoinductivity of Demineralized Bone Matrix with Noggin Suppression in Polymer Matrix. Advanced Biology, 5(1):2000135, 2021. *Co-corresponding author
3. Kim S, Fan J, Lee C-S, Chen C, Lee M. Sulfonate Hydrogel-siRNA Conjugate Facilitates Osteogenic Differentiation of Mesenchymal Stem Cells by Controlled Gene Silencing and Activation of BMP Signaling. ACS Appl. Bio Mater., 4(6):5189–5200, 2021.
4. Fan J, Lee CS, Kim S, Zhang X, Pi-Anfruns J, Guo M, Chen C, Rahnama M, Li J, Wu BM, Aghaloo T, Lee M. Trb3 Controls Mesenchymal Stem Cell Lineage Fate and Enhances Bone Regeneration by Scaffold-Mediated Local Gene Delivery. Biomaterials, 264:120445, 2021.
5. Kim S, Fan J, Lee CS, Chen C, Bubukina K, Lee M. Heparinized Chitosan Stabilizes the Bioactivity of BMP-2 and Potentiates the Osteogenic Efficacy of Demineralized Bone Matrix. Journal of Biological Engineering, 14:6, 2020.
6. Zhang X, Fan J, Lee CS, Kim S, Chen C, Aghaloo T, Lee M. Apatite-binding nanoparticulate agonist of hedgehog signaling for bone repair. Advanced Functional Materials, 30(12):1909218, 2020.
7. Kim S, Fan J, Lee CS, Lee M. Dual Functional Lysozyme-Chitosan Conjugate for Tunable Degradation and Antibacterial Activity. ACS Applied Bio Materials, 3(4):2334-2343, 2020.
8. Zhang X, Fan J, Lee CS, Kim S, Chen C, Lee M. Supramolecular Hydrogels based on Nanoclay and Guanidine-Rich Chitosan: Injectable and Moldable Osteoinductive Carriers. ACS Applied Materials & Interfaces, 12(48):16088-16096, 2020.
9. Lee CS, Kim S, Fan J, Hwang HS, Aghaloo T, Lee M. Smoothened Agonist Sterosome Immobilized Hybrid Scaffold for Bone Regeneration. Science Advances, 6(17):eaaz7822, 2020.
10. Lee CS, Hwang HS, Kim S, Fan J, Aghaloo T, Lee M. Inspired by nature: facile design of nanoclay-organic hydrogel bone sealant with multifunctional properties for robust bone regeneration. Advanced Functional Materials, 30(43):2003717, 2020.
11. Fan J*, Lee CS*, Kim S, Chen C, Aghaloo T, Lee M. Generation of Small RNA- Modulated Exosome Mimetics for Bone Regeneration. ACS Nano,14(9):11973-11984, 2020. *Equal contribution
12. Wang G*, Shen J*, Sun J*, Jiang Z*, Fan J, Wang H, Yu S, Long Y, Liu Y, Bao H, Zhang K, Han K, Zhu M, Zheng Y, Lin Z, Jiang C, and Guo M. Cyclophilin A maintains glioma-initiating cell stemness by regulating wnt/β-catenin signaling. Clinical Cancer Research, 23(21):6640-6649, 2017. *Co-first author
13. Cui ZK, Sun JA, Baljon JJ, Fan J, Kim S, Wu BM, Aghaloo T, Lee M. Simultaneous delivery of hydrophobic small molecules and siRNA using Sterosomes to direct mesenchymal stem cell differentiation for bone repair. Acta Biomaterialia, 58:214-224, 2017.
14. Fan J, Sun L, Chen X, Qu L, Li H, Liu X, Zhang Y, Cheng P, Fan H. Implementation of stratified approach and gene immobilization to enhance the osseointegration of silk-based ligament graft. Journal of Materials Chemistry B, 5:7035-7050, 2017.
15. Fan J, Guo M, Im C, Pi-Anfruns J, Cui Z, Kim S, Wu BM, Aghaloo T, Lee M. Enhanced mandibular bone repair by combined treatment of bone morphogenetic protein-2 and small molecule phenamil. Tissue Engineering Part A, 23(5-6):195-207, 2017. Cover Article
16. Fan J, Pi-Anfruns J, Guo M, Im DCS, Cui ZK, Kim S, Wu BM, Aghaloo TL, Lee M. Small molecule-mediated tribbles homolog 3 promotes bone formation induced by bone morphogenetic protein-2. Sci Rep., 7(1):7518, 2017
17. Zou TQ, Fan J, Fartash A, Liu H, Fan Y. Cell-based strategies for vascular regeneration. Journal of Biomedical Materials Research Part A, 104(5):1297-314, 2016
18. Yao Y, Fan J, Im CS, Liu H, Fan Y. Biomolecule modification of scaffolds in vascular regeneration. Journal of Biomaterials and Tissue Engineering, 6:1-9, 2016.
19. Kim S, Cui ZK, Fan J, Fartash A, Aghaloo T, Lee M. Photocrosslinkable chitosan hydrogels functionalized with the RGD peptide and phosphoserine to enhance osteogenesis. Journal of Materials Chemistry B, 4:5289-98, 2016.
20. Fan J*, Wang DA, Liu H, Fan H, Yang F. Stem Cells in Musculoskeletal Regeneration: From Benchtop to Bedside. Stem Cells Int., 2016:8432314, 2016. *Corresponding author
21. Sun L, Qu L, Zhu R, Li H, Xue Y, Liu X, Fan J, Fan H. Effects of mechanical stretch on cell proliferation and matrix formation of mesenchymal stem cell and anterior cruciate ligament fibroblast. Stem Cells Int., 2016 (2016), Article ID 9842075.
22. Fan J, Im C, Guo M, Cui Z.-K, Fartash A, Kim S, Patel N, Bezouglaia O, Wu BM, Wang C.-Y, Aghaloo T, Lee M. Enhanced osteogenesis of adipose-derived stem cells by regulating BMP signaling antagonists and agonists. Stem Cells Translational Medicine, 5:539-551, 2016.
23. Li H*, Fan J*, Sun L, Liu X, Cheng P, Fan H. Functional regeneration of ligament- bone interface using a triphasic silk-based graft. Biomaterials, 106:180-92, 2016. *Co-first author
24. Choi B, Cui ZK, Kim S, Fan J, Wu B, Lee M. Glutamine-chitosan modified calcium phosphate nanoparticles for efficient siRNA delivery and osteogenic differentiation. Journal of Materials Chemistry B, 3:6448-55, 2015.
25. Choi B, Kim S, Fan J, Kowalski T, Petrigliano F, Evseenko D, Lee M. Covalently conjugated transforming growth factor-β1 in modular chitosan hydrogels for the effective treatment of articular cartilage defects. Biomaterials Science, 3:742-52, 2015.
26. Fan J, Im C, Cui Z.-K, Guo M, Bezouglaia O, Fartash A, Lee J, Nguyen J, Wu B, Aghaloo T, Lee M. Delivery of phenamil enhances BMP-2-induced osteogenic differentiation of adipose derived stem cells and bone formation in calvarial defects. Tissue Engineering Part A, 21(13-14):2053-2065, 2015.
27. Cui ZK, Fan J, Kim S, Bezouglaia O, Fartash A, Wu BM, Aghaloo T, Lee M. Delivery of siRNA via cationic Sterosomes to enhance osteogenic differentiation of mesenchymal stem cells. Journal of Controlled Release, 217:42-52, 2015.
28. Fan J, Park H, Lee M, Bezouglaia O, Fartash A, Kim J, Aghaloo T, Lee M. Adipose derived stem cells and BMP-2 delivery in chitosan-based 3D constructs to enhance bone regeneration in a rat mandibular defect model. Tissue Engineering Part A, 20(15-16):2169-79, 2014.
2009-2013
1. Liu TM, Ng WM, Tan HS, Vinitha D, Yang Z, Fan J, Zou Y, Hui JH, Lee EH, Lim B. Molecular basis of immortalization of human mesenchymal stem cells by combination of p53 knockdown and human telomerase reverse transcriptase overexpression. Stem Cells and Development, 15:22(2):268-78, 2013.
2. Park H, Choi B, John N, Fan J, Shafi S, Klokkevold P, Lee M. Anionic carbohydrate-containing chitosan scaffolds for bone regeneration. Carbohydrate Polymers, 97:587-96, 2013.
3. Fan J, Park H, Tan S and Lee M. Enhanced osteogenesis of adipose derived stem cells with noggin suppression and delivery of BMP-2. Plos One, 15:8(8):e72474, 2013.
4. Wang XP, Fan J. Molecular genetics of supernumerary tooth formation. Genesis, 49(4):261-77, 2011. Citations>240
5. Yao Y, Zhang F, Zhou R, Su K, Fan J, Wang DA. Effects of combinational adenoviral vector-mediated TGF beta 3 transgene and shRNA silencing type I collagen on articular chondrogenesis of synovium-derived mesenchymal stem cells. Biotechnology and Bioengineering, 106(5):818-28, 2010.
6. Yan LP, Wang YJ, Ren L, Wu G, Caridade SG, Fan J, Wang LY, Ji PH, Oliveira JT, Mano JF, Reis RL. Genipin-cross-linked collagen/chitosan biomimetic scaffolds for articular cartilage tissue engineering applications. Journal of Biomedical Materials Research Part A, 95(2):465-75, 2010.
7. Varshney RR, Zhou R, Hao J, Yeo SS, Chooi WH, Fan J, Wang DA. Chondrogenesis of synovium-derived mesenchymal stem cells in gene-transferred co-culture system. Biomaterials, 31(26):6876-91, 2010.
8. Fan J, Ren L, Liang R, Gong Y, Cai D and Wang DA. Chondrogenesis of synovium- derived mesenchymal stem cells in photopolymerizing hydrogel scaffolds. Journal of Biomaterials Science-Polymer Edition, 21(12):1653-67, 2010.
9. Fan J, Gong Y, Ren L, Varshney RR, Cai D, Wang DA. In vitro engineered cartilage using synovium-derived mesenchymal stem cells with injectable gellan hydrogels. Acta Biomaterialia, 6 (3):1178-1185, 2010.
10. Fan J, Varshney RR, Ren L, Cai D, Wang DA. Synovium-derived mesenchymal stem cells: a new cell source for musculoskeletal regeneration. Tissue Engineering Part B Rev., 15(1):75-86, 2009. Citations>200. Editors’ Picks article